P2Et Phosphazene: A Versatile Base for Room-Temperature Pd-Catalyzed Cross-Couplings
P2Et superbase enables palladium-catalyzed C-C, C-N, C-O cross-couplings of aryl halides at room temp. Ideal for synthesizing complex molecules.
Abstract
The non-nucleophilic organic superbase P2Et phosphazene can enable a broad range of palladium-catalyzed cross-coupling reactions, including C-C, C-N, and C-O couplings of aryl chlorides, bromides, and iodides at room temperature. The mildness and substrate compatibility of this chemistry can deliver immediate synthetic utility for the preparation of complex molecules.
Publication
Full Headline:
P2Et Phosphazene: A Mild, Functional Group Tolerant Base for Soluble, Room Temperature Pd-Catalyzed CN, CO, and CC Cross-Coupling Reactions
Keywords:
Coupling reactions, Organic compounds, Organic reactions, Palladium, Substitution reactions
Author:
Santanilla, A.B., et.al.
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